研究领域：合成生物学 研究方向：生物催化工程；代谢工程 主持项目 1）L-天冬氨酸α-脱羧酶中试生产工艺研究，山东省重点研发项目 2）壳聚糖酶菌株及生产工艺，横向课题 3）生物医药及中间体产品的生产关键技术开发，横向课题 4) 氨基酸发酵关键技术开发，横向课题 5）谷氨酸发酵工艺优化，横向课题 代表论文 1) Feng, Z., Chen, G., Zhang, J. et al. Characterization and Complete Genome Analysis of the Carbazomycin B-Producing Strain Streptomyces luteoverticillatus SZJ61. Curr Microbiol (2019) 76: 982–987. 2) Feng, Z., Zhang, J., Chen, G. et al. Extracellular Expression of L-Aspartate-α-Decarboxylase from Bacillus tequilensis and Its Application in the Biosynthesis of β-Alanine.Appl Biochem Biotechnol (2019) 189: 273–283. 3) Huang Run#, Feng Zhibin#, Chi Xiaoyan#, et al. Pyrrolnitrin is more essential than phenazines for Pseudomonas chlororaphis G05 in its suppression of Fusarium graminearum. Microbiological Research, 2018, 215:55-64. 4）Tianqi Yu, Yifan Yin, Yihe Ge, Shiwei Cheng, Xingxiao Zhang, Zhibin Feng (通讯作者), Juan Zhang. Enzymatic production of 4-hydroxyphenylacetaldehyde by oxidation of the amino group of tyramine with a recombinant primary amine oxidase. Process Biochemistry, 2020, 92: 105-112. 5）Xinyu Zou, Laixian Guo, Lilong Huang, Miao Li, Sheng Zhang, Anren Yang, Yu Zhang, Luying Zhu, Hongxia Zhang, Juan Zhang, Zhibin Feng (通讯作者). Pathway construction and metabolic engineering for fermentative production of β-alanine in Escherichia coli. Applied Microbiology and Biotechnology, 2020, 104:2545–2559. 6）Feng Z, Xu M, Yang J, Zhang R, Geng Z, Mao T, Sheng Y, Wang L, Zhang J and Zhang H (2022) Molecular characterization of a novel strain of Bacillus halotolerans protecting wheat from sheath blight disease caused by Rhizoctonia solani Kühn. Front. Plant Sci. 13:1019512. doi: 10.3389/fpls.2022.1019512 授权发明专利 1）一种酶法制备左旋多巴的方法. ZL201510129123.X 2）一株高产天冬氨酸脱羧酶的菌株及用于生产丙氨酸的方法. ZL201510973906.6 3）类芽孢杆菌及其生物防治制剂的制备方法. ZL201910287097.1 4) 一株产腈水解酶的菌株及用于生产对羟基苯乙酰胺的方法. ZL201711061890.7 5）一株产酪氨酸解氨酶的菌株及应用. ZL202010540640.7 6）一种酶法制备4-羟基苯乙醛的方法. ZL201910856791.0 7）一株产还原性脱卤素酶的菌株及其应用. ZL202110223546.3 8）一种藤黄轮丝链霉菌及其生物防治制剂和应用. ZL201810032717.2 9）一种D-氨基酸氧化酶突变体、工程菌及应用. ZL202210541035.0 10）一种用于提高β-丙氨酸产量的发酵培养基及应用方法. ZL202110104824.3 11）酪氨酸酚裂解酶的胞外表达及其应用. ZL201810589389.6 |
